In order for pharmaceuticals to be safe, they must be clean of pollutants. Carbon dioxide can be used to make the purification process more environmentally friendly, which may seem paradoxical since carbon dioxide is usually associated with a negative climate impact. However, if carbon dioxide is recovered from other existing processes and if the use of environmentally hazardous organic solvents is reduced, large gains can be made both economically and environmentally.
“More knowledge of how the separation system works makes it easier to predict how to design an optimal system,” says Emelie Glenne, who recently defended her doctoral thesis in chemistry.
Chromatography is a separation technique used both to purify samples and to analyse which substances a sample contains. The method is based on the substances to be separated being distributed between a stationary and a mobile phase. In her thesis, Emelie Glenne has focused on so-called supercritical fluid chromatography, SFC.