Preparative chromatography and introduction to process analysis
15.0 ECTS creditsInstruction is in the form of lectures, exercises, laboratory sessions, seminars, and a project. Students
are expected to study certain units on their own.
The course comprises two modules: preparative chromatography for small and large molecules and process analysis. The preparative chromatography module also includes a project.
The preparative chromatography module covers the following:
- Introduction to equipment for chromatographic purification and processes at different scale, both batch and continual elution
- In-depth study of different separation mechanisms related to stationary phase chemistry, adsorption isotherms, column models, and process optimisation
- Introduction to numerical simulation of separation processes and the use of column models and adsorption models for calculation of design parameters for different separation processes
- Empirical and numerical modelling and optimisation of separation processes
The project included in the preparative chromatography module covers the following:
- Introduction to the use of chromatographic purification equipment
- Exercises in numerical and empirical optimisation of separation problems
- A project which includes selection of a separation problem, literature study, design of a separation strategy, calculations, experimental characterisation of the separation system (if applicable), optimisation of the separation, analysis of the results, a written report, and an oral presentation
All project components involve mandatory attendance and active participation.
The process analysis module covers the following:
- Introduction to common techniques and sensors used in PAT, plus related theories
- Sensor strategies and sampling strategies for measurements in process analysis
- Processing of sensor data using for instance chemometric methods
Laboratory sessions and seminars involve mandatory attendance and active participation.
are expected to study certain units on their own.
The course comprises two modules: preparative chromatography for small and large molecules and process analysis. The preparative chromatography module also includes a project.
The preparative chromatography module covers the following:
- Introduction to equipment for chromatographic purification and processes at different scale, both batch and continual elution
- In-depth study of different separation mechanisms related to stationary phase chemistry, adsorption isotherms, column models, and process optimisation
- Introduction to numerical simulation of separation processes and the use of column models and adsorption models for calculation of design parameters for different separation processes
- Empirical and numerical modelling and optimisation of separation processes
The project included in the preparative chromatography module covers the following:
- Introduction to the use of chromatographic purification equipment
- Exercises in numerical and empirical optimisation of separation problems
- A project which includes selection of a separation problem, literature study, design of a separation strategy, calculations, experimental characterisation of the separation system (if applicable), optimisation of the separation, analysis of the results, a written report, and an oral presentation
All project components involve mandatory attendance and active participation.
The process analysis module covers the following:
- Introduction to common techniques and sensors used in PAT, plus related theories
- Sensor strategies and sampling strategies for measurements in process analysis
- Processing of sensor data using for instance chemometric methods
Laboratory sessions and seminars involve mandatory attendance and active participation.
Progressive specialisation:
A1N (has only first‐cycle course/s as entry requirements)
Education level:
Master's level
Admission requirements
A Bachelor degree in Chemistry or registered for 90 ECTS credits in Chemistry, with 75 ECTS credits completed, and upper secondary level Swedish 3 or Swedish as a second language 3 and English 6, or equivalent
Selection:
Selection is usually based on your grade point average from upper secondary school or the number of credit points from previous university studies, or both.
Course code:
KEAE30
The course is not included in the course offerings for the next period.